The little known nutrient that’s growing my daughter new mitochondria | PQQ


We all have them.

We all need them.

We need them especially in order to digest some of the biology textbook reminiscent explanations of what they do!

But we’ve got even the most mito-challenged, fatigued among you covered with this two-minute, easy-to-follow video that explains why mitochondria are the powerhouses of our cells and what can happen if they aren’t optimally functioning.

Mitochondrial dysfunction

Mitochondrial disease and dysfunction are both serious cause for attention because their effects are so far reaching. Anyone with poorly functioning or a decreased quantity of mitochondria can suffer from a wide variety of symptoms, including:

• Fatigue, weakness, loss of muscle coordination • Neurological problems, seizures, strokes, headaches • Autistic-like features • Visual and/or hearing problems • Developmental delays, learning disabilities • Heart, liver or kidney disease • Gastrointestinal disorders, constipation • Diabetes • Increased risk of infection • Thyroid and/or adrenal dysfunction • Autonomic dysfunction • Neuropsychiatric symptoms, memory loss, ADHD, OCD, anxiety, depression

Not surprisingly, the tissues and organs with the greatest density of mitochondria, our brain and muscles, are the ones that suffer the most in mito dysfunction. A mito cocktail of supplements; CoQ10, l-carnitine, b-vitamins and antioxidants help nourish our mitochondria and ensure our cells aren’t running on empty. And they are essential! But something none of them can do is generate new mitochondria.

Pyrroloquinoline Quinone (PQQ)

In the world of treating mito dysfunction, the introduction of PQQ, a next-generation coenzyme capable of growing new mitochondria, is a game changer.

It’s been called the “fountain of youth” for mitochondria because while supplements such as CoQ10 help optimize mitochondrial function, PQQ activates the genes that govern mitochondrial reproduction, protection, and repair.

Increasing your mitochondria count provides your cells with more energy, much like a larger horsepower engine. In this analogy, the fuel you add from a mito cocktail can only help so much if the quantity of mitochondria (your horsepower) is not also increased. With PQQ your cells are supercharged.

But there’s more! In addition to generating new mitochondria, PQQ also has the power to calm and heal our brain’s neurotransmitters. It does this by preventing overstimulation of our NMDA receptors (often occurring from excess glutamate) and reducing excitotoxicity, in turn improving the symptoms of many neurological conditions and even promoting better sleep.

Still another benefit is PQQ’s ability to protect the brain against damage from certain environmental toxins. A recent study showed it significantly reduced mercury induced neuronal toxicity.

Did we have you at mercury? Thought so!

You can probably guess that research and articles about the myriad benefits of PQQ are a plenty. Please read 11 Proven Health Benefits of PQQ to learn about how PQQ can also:

Decrease Inflammation – Increase Nerve Growth Factor – Improve Sleep, Mood and Fatigue – Decrease Inulin Resistance – Improve Memory and Reasoning – Improve Immune Health – And more

Potential Physiological Importance of Pyrroloquinoline Quinone is a well written scholarly review authored by three PhD researchers.

Regarding Caroline

Almost four months ago, Caroline experienced a severe PANS flare. It was the first episode following an initial diagnosis in 2011 and came on with a vengeance. We’ve been working diligently to heal her and added PQQ two months ago, along with other treatments.  It’s impossible to pinpoint it’s exact effect, but I believe it’s been significant in the healing process. I can report that from a list of 20+ symptoms and days we couldn’t leave the house, only 2 of them remain and she’s happy to be feeling better!

How much do we need?

PQQ can be found in many foods, however the levels are a fraction of what’s needed to achieve benefits found in the studies. Some of the research has been conducted with 20 mg of PQQ in adult participants. They found that the effects were even more dramatic when administered with coQ10, however you can also use PQQ alone.

*If you’re adding them both, I recommend to do so separately. While helpful for most, CoQ10 / Ubiquinol (or too much of it), can make certain kids more stimmy or add a ‘wired’ feeling. I haven’t heard of PQQ alone having that effect.

A dose of 0.2-0.3 mg/kg per day of PQQ has been studied here and is generally what I suggest.

Caroline takes 7mg PQQ – she is 75 lbs (34kg).

*I empty a small portion of the contents of a 10 mg capsule to get to a 7mg dose of BioPQQ. There are many brands and variations of this supplement and it’s generally tasteless.

It’s been said that supplementing with PQQ can feel like a power surge for your mind and body. I’ve taken it and can attest to noticeably greater energy and mental clarity.

Since there never seem to be enough hours in the day, those benefits alone make it worthwhile… but when you see that it can help calm and heal intense neurological issues for your child, well, then you really have to write a blog about it.


4For additional blog posts by Rebecca Ferguson – Regarding Caroline • click here

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39 thoughts on “The little known nutrient that’s growing my daughter new mitochondria | PQQ

Add yours

  1. Thanks a lot for writing this great blog post. I have a 7 year old daughter on the spectrum. She has mito issues and MTHFR gene mutation as well (one copy). I am new in the biomed journey and my daughter has been on coq10 30mg and l-carnitine 500 for the last 5 months. I have seen good improvements so far. Can I add in PQQ right away? Is it really safe and free of side effects? I’m always nervous about starting something new. Please guide.

    Caroline is so beautiful. Hope she gets the best things in life ☺

    Liked by 1 person

  2. I am on a Facebook Group for victims of Cipro Toxicity – we are suffering daily. Our mitochondria system has been severely compromised.
    If this product you are suggesting helps mitochondria – how come no doctors will tell us this? I’ve been to numerous doctors and so has thousands of others — we’ve all seen MD’s, Neurologists, Naturopathic Doctors, chiropractors, physical therapists. They don’t help us — the closest any one of them has been a Naturopath that did explain to me that my Mitochondria is the powerhouse of energy in my body and it has been damaged — but he never suggested taking CoQ10 nor PQQ

    Please understand that I am NOT DOUBTING your advice — I just am having a hard time with doctors for the last 18 months!

    How did you discover this product? Who recommended it to you and where did you purchase it? Any more information you can provide will be greatly appreciated.

    P.s. I found your blog because another Cipro victim posted it on our FB Group.
    Thank you – Leigh Ann


    1. I’m so sorry to hear about your struggle. Cipro can have some very terrible effects. I’m not sure why your doctors wouldn’t recommend a Mito cocktail of supplements, they are very common. My daughter’s doctor knows of them and PQQ has many studies backing it up, you can click on any of the green links in this blog for the research studies.

      You can purchase many different brands on amazon or at any health foods retailer, Whole Foods even carries it. I would be sure to also use at least CoQ10/ubiquinol and also look into the other Mito cocktail supplements (see link in blog). I wish you all the best! 💛


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